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Fibrocartilage

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Fibrocartilage
File:Gray295.png
White fibrocartilage from an intervertebral fibrocartilage.
File:Gray321.png
Symphysis pubis exposed by a coronal section. (Pubic symphysis visible at center left.)
Gray's subject #68 281

White fibrocartilage consists of a mixture of white fibrous tissue and cartilaginous tissue in various proportions. It owes its flexibility and toughness to the former of these constituents, and its elasticity to the latter. It is the only type of cartilage that contains type I collagen in addition to the normal type II.

Fibrocartilage is found in the pubic symphysis, the annulus fibrosus of intervertebral discs, meniscus, and the TMJ. During labor, relaxin loosens the pubic symphysis to aid in delivery, but this can lead to later joint problems.

Formation as a repair mechanism

If normal cartilage is torn all the way down to the bone, the blood supply from inside the bone is sometimes enough to start some healing inside the lesion. In cases like this, the body will form a scar in the area using a special type of cartilage called fibrocartilage. Fibrocartilage is a tough, dense, fibrous material that helps fill in the torn part of the cartilage. Yet it's not an ideal replacement for the smooth, glassy articular cartilage that normally covers the surface of the knee joint.

Microscopic appearance

When examined under the microscope it is found to be made up of fibrous connective tissue arranged in bundles, with chondrocytes between the bundles; the cells to a certain extent resemble tendon cells or dense regular connective tissue, but may be distinguished from them by being surrounded by a concentrically striated area of cartilage matrix, their lacunae, and by being less flattened, bent over.

Pathology

File:Degenerative disc disease - high mag.jpg
Micrograph showing a fragment of a intervertebral disc demonstrating degenerative fibrocartilage with loss of nuclei and nests of chondrocytes, as seen in degenerative disc disease. HPS stain.

Degeneration of fibrocartilage is seen in degenerative disc disease.

See also

External links

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained within it may be outdated.Template:Musculoskeletal-stub