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'Misalignment of the vertebrae is a concept that, is similar to the idea of "Bone out of place" a/k/a "BOOP", and is an arcane concept not supported by scientific research. It has been largely supplanted by a far more scientific idea that vertebral joints can develop a dysfunctional mobility and "lock" within their range-of-motion, yielding; inflammation of the joint capsule and possible neurological dysfunction.